I assume you mean an oxy-acteleye setup... Besides having a little steeper learning curve than Mig or even Arc, the biggest drawback for us (4wheelers) is going to be lack of penetration. Gas works great for body or exhaust work, but when you're routinely dealing with 1/4" and thicker, you'll want better penetration.

sure the torch and regulators are only about $150-200, but thanks will cost you at least $400-500 empty. sure you can lease them and costs are not as bad, but if you compair outright purchase, you can easily have a nice MIG machine for the cost.

-Rob