I see all this, but there are a few guys on customtacos that are running 15psi boost on their stock long block 2rz's (with metal head gaskets and head studs) and makign 250whp no problem, and they also have a high compression ratio.
Hell, they're turboing completely stock 3.4's and making 350hp.. all of these intercooled of course... and no problems.
Howcome the 22re is so troublesome with boost?

89 4Runner
3" BL, M/T locks, 33"bfg mt, bilstein, Kayline, tubebumper, toyotafiberglass panels
TBI: Elocker,3.4 w/ORS,b+b,S2Sstg2cams,arias pistons,P+P intake,TRDs/c,URDpullies+7th,downey headers,MAPECU2,WEGO WB, SupraMAF,walboro255,stg4clutch, EPaOo2 sim