I've got just over 160K on my T and it is running as smooth and getting as good mileage as ever! I got almost 22MPG on an all interstate tank a couple of weeks ago and almost 21MPG on a tank with a mix of interstate and mountain roads (MD, WV). Around town (for me 50/50 interstate/stop and go) I can get 18 with no boats on top - with boats it can drop to 16-17.

96 T100 Titan Xcab V6 2WD,Powertrax No-Slip Diff, buckets, mini-mods...
http://picasaweb.google.com/scott.broam/TruckProjects#