If you have patience and aren't in a hurry, you can leave the rad in even with big hands. It does make it a little tight, but not impossible, you may want to remove the fan shroud if you have one for more room.

More than tread lightly. Leave it like you were never there, nor anyone else.
'90 X-cab 4.88's 33 BFG AT's, rr ARB, Headers, Ignition upgrade, cold air induction.
'91 X-cab 5.29's 315's BFG MT's, rr ARB, custom bumper and flatbed