Big filters will fit. 22RE w/AC, etc. It will fit fine. I ran a WIX 51515, basically same as the PH8 Fram units, on mine while I was waiting for the parts store to get the right block adapter for my relocation kit.

'90 Pickup 22RE 4.30's, 31 STT's, MossyRock Sliders
'90 2wd xtraCab, getting a heart transplant
'88 4Runner with a thrown rod, waiting in the wings