The Isuzus use two variations on the MUA transmissions behind the 2.6 and the 2.8. Both use a hydraulic clutch.

On the 2.6, the slave cylinder is on the right (passenger) side of the tranny and on the 2.8, the slave is on the left (driver) side.

To the best of my knowledge, Isuzu never used the T-5 behind either (I am sitting here with the FSM and it only lists the MUA transmission).

In addition, the tranfer case is integral with the MUA, whether in the 2.6 or the 2.8. Assuming that you want to keep the 4X4 capability, you are probably in trouble using the tranny out of an S-10, as I believe that the S-10 uses a driver's side drop for the front drive shaft, while all the Isuzus use a passenger side drop.

Even if you want to go to 2X4, you are going to have to fabricate something for a transmission cross member.