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Les, we did the Dedeckera canyon route the other way, from north to south, and we went through the marble steps up. Most our vehicles did not have the lockers and they were fine - may be a few extra approaches, but fine.
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I've run Dedecker canyon in my f250 4x4 diesel pickup in both directions; no lift, no locker, no problems.

'89 Raider V6, AT, SAS'ed, Dana 44 front & rear, 5:38 gears, NP 231 T-case.
'97 Montero SR, cold weather package, 4.90 R&P, BATTLEZ suspension w/ 2" lift, JAOS grill guard & under body protection, custom rock sliders.